Chromogenic depsipeptide substrates for beta-lactamases and penicillin-sensitive DD-peptidases.

نویسندگان

  • M Adam
  • C Damblon
  • B Plaitin
  • L Christiaens
  • J M Frère
چکیده

Various ester and thioester derivatives of hippuric acid have been prepared which were substrates of both beta-lactamases and DD-peptidases. The thioesters were more rapidly hydrolysed by nearly all the enzymes. Surprisingly, the enzymes acted rather efficiently on substrates which did not contain any chiral centre.

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عنوان ژورنال:
  • The Biochemical journal

دوره 270 2  شماره 

صفحات  -

تاریخ انتشار 1990